Protective effect of lappaconitine on Freund's complete adjuvant-induced arthritis exerted through P2X7 receptor-mediated regulation of M1/M2 balance in rats.

Our findings indicate that the notable therapeutic and analgesic effects of LA on AIA rats are exerted through balancing the M1/M2 ratio, probably via P2X7r.

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Publication Details

Journal
PubMed
Published
2025-02-01
DOI
https://doi.org/10.19852/j.cnki.jtcm.2025.01.004
Citations
1
Primary Topic
Adenosine and Purinergic Signaling
Type
article
Field-Weighted Citation Impact
1.12
Controls
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article

Protective effect of lappaconitine on Freund's complete adjuvant-induced arthritis exerted through P2X7 receptor-mediated regulation of M1/M2 balance in rats.

O U Shan, Qi Feng, Zhang Pengqiang, Huang Weiyan
1 citations
PubMed
Adenosine and Purinergic Signaling
1.12
article

Protective effect of lappaconitine on Freund's complete adjuvant-induced arthritis exerted through P2X7 receptor-mediated regulation of M1/M2 balance in rats.

O U Shan, Qi Feng, Zhang Pengqiang, Huang Weiyan
article en
1 citations

Abstract

Our findings indicate that the notable therapeutic and analgesic effects of LA on AIA rats are exerted through balancing the M1/M2 ratio, probably via P2X7r.

PubMedVol. 45(1)
First Affiliated Hospital of Chengdu Medical College (CN), Chengdu University of Traditional Chinese Medicine (CN)
Openalex Percentile: Top 28%
Adenosine and Purinergic Signaling
1.12
DOIOpen Access PDFOpenAlex
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