Plasma brain-derived neurotrophic factor concentrations are elevated in community-dwelling adults with sarcopenia
Circulating BDNF concentrations are elevated in community-dwelling men and women with sarcopenia, which may reflect increased neuromuscular remodelling in these people. Our findings complement existing data, supporting the presence of an intricate relationship between neural integrity and skeletal muscle health. Future studies are needed to establish the mechanistic pathways that may underpin the associations.
Authors
- Evgeniia Motanova (ORCID: https://orcid.org/0000-0002-2200-9191)
- Jedd Pratt (ORCID: https://orcid.org/0000-0002-7410-078X)
- Giuseppe De Vito (ORCID: https://orcid.org/0000-0002-6855-9180)
- Marco Narici (ORCID: https://orcid.org/0000-0003-0167-1845)
- Colin Boreham (ORCID: https://orcid.org/0000-0001-8885-9677)
Institutions
- University College Dublin (IE)
- Manchester Metropolitan University (GB)
- University of Padua (IT)
Publication Details
- Journal
- Age and Ageing
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1093/ageing/afaf024
- Citations
- 9
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 10.48