Healthcare Workers’ Knowledge, Practice and Associated Factors Towards Prevention of Central Line-Associated Blood Stream Infections in Cardiac Centers of Addis Ababa, Ethiopia, 2024

Introduction: Preventing central line-associated bloodstream infections in healthcare settings reduces morbidity, mortality, and healthcare costs. This study aimed to assess healthcare workers' knowledge, practice, and associated factors regarding central line-associated bloodstream infection prevention in Addis Ababa cardiac units. Methods: From May 20 to June 20, 2024, in seven cardiac centers in Addis Ababa, we employed a hospital-based cross-sectional study design and participants were chosen by simple random sampling. Data were entered using EpiData version 3.1 and exported and analyzed using SPSS version 25. A multivariable logistic regression analysis and variables with p-value <0.05 were considered as statistically significant. Results: The magnitude of healthcare workers' knowledge and practice towards the prevention of central line-associated bloodstream infections was 85.8% (95% CI: 82.38%, 89.22%) and 73.5% (95% CI: 69.17%, 77.83%), respectively. After adjusted analysis, a bachelor's degree or higher (AOR: 2.086, 95% CI: 1.127, 3.860), participating in a peer education program (AOR: 2.365, 95% CI: 1.274, 5.713), and training (AOR: 2.820, 95% CI: 1.392, 9.590) were factors associated with knowledge. Male sex (AOR: 2.059, 95% CI: (1.223, 3.467)), more than five years of work experience (AOR: 2.073, 95% CI: (1.149, 3.739)), and training (AOR: 3.857, 95% CI: (2.180, 6.826)) were factors associated with practice. Conclusions: More than three-fourths and approximately three-fourths of health care workers in cardiac centers in Addis Ababa had good knowledge and had good practice towards prevention of central line-associated bloodstream infections. Healthcare professionals involved in patient care should receive ongoing, updated CLABSI prevention training integrated into professional development initiatives.