Inflammatory Biomarkers Demonstrate Predictive Capacity for Mortality in COVID-19-Related ARDS Patients Receiving High-Dose Corticosteroids: A Longitudinal Analysis
In COVID-19 ARDS patients receiving HDS, several clinically available inflammatory biomarkers moderately predicted all-cause-hospital-mortality after the start of HDS, particularly on days 6 and 7. NLR demonstrated the most consistent association with mortality over time. The use of these markers requires validation in larger cohorts.
Authors
- Katrijn Daenen (ORCID: https://orcid.org/0009-0003-5664-5393)
- Anders C. Boyd (ORCID: https://orcid.org/0000-0001-9512-8928)
- Virgil A. S. H. Dalm (ORCID: https://orcid.org/0000-0001-5945-4435)
- Sara C. M. Stoof (ORCID: https://orcid.org/0000-0003-0774-1496)
- Eric C. M. Van Gorp (ORCID: https://orcid.org/0000-0001-6415-6678)
- Henrik Endeman (ORCID: https://orcid.org/0000-0002-2011-5169)
- Lieuwe D. J. Bos (ORCID: https://orcid.org/0000-0003-2911-4549)
- Jilske Huijben (ORCID: https://orcid.org/0000-0002-2892-5406)
- Diederik A M P J Gommers (ORCID: https://orcid.org/0000-0001-6808-7702)
Institutions
- Erasmus MC (NL)
- OLVG (NL)
- Stichting HIV Monitoring (NL)
- GGD Amsterdam (NL)
- Amsterdam University Medical Centers (NL)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-02-01
- DOI
- https://doi.org/10.2147/jir.s502188
- Citations
- 3
- Primary Topic
- COVID-19 Clinical Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 4.19
Funders
- ZonMw