Metabolomic analysis of rat arterial serum under hypobaric hypoxia: Adaptive regulation of physiological systems by metabolic reprogramming
Short-term hypobaric hypoxia exposure significantly altered the metabolite profiles in the arterial serum samples of rats, revealing adaptive metabolic reprogramming in energy metabolism, redox balance, immune function, endocrine regulation, and neurological systems.
Authors
- Baozhong Xin
- Zihao Zhang (ORCID: https://orcid.org/0000-0002-5898-7704)
- Erjia Zhu (ORCID: https://orcid.org/0000-0002-6712-5196)
- Bing Li (ORCID: https://orcid.org/0000-0001-6504-2728)
- Xiaoqin Ha (ORCID: https://orcid.org/0000-0002-3280-413X)
- Bin Xie (ORCID: https://orcid.org/0000-0003-2034-0160)
- Drosdowsky Ma
Institutions
- Gansu University of Traditional Chinese Medicine (CN)
- People's Liberation Army 401 Hospital (CN)
- The First People's Hospital of Tianmen (CN)
- Gansu Great Wall Electrical and Electronics Engineering Research Institute (CN)
Publication Details
- Journal
- Biochemistry and Biophysics Reports
- Published
- 2025-02-18
- DOI
- https://doi.org/10.1016/j.bbrep.2025.101943
- Primary Topic
- High Altitude and Hypoxia
- Type
- article
- Field-Weighted Citation Impact
- 0.00