Aged‐Related Fibroblast Activation Protein Expression in Skeletal Muscles Evaluated by PET Imaging
This study demonstrates an age-related increase in FAPI uptake in skeletal muscle, correlated with changes in muscle density and fat infiltration. The role of FAP extends beyond pathology to normal muscle, indicating broader biological functions. Accordingly, FAPI PET shows promise for assessing age-related muscle health and quality.
Authors
- Gi Jeong Cheon (ORCID: https://orcid.org/0000-0002-1360-5186)
- Minseok Suh (ORCID: https://orcid.org/0000-0002-6932-8552)
- Hongyoon Choi (ORCID: https://orcid.org/0000-0002-8895-2449)
- Joonhyung Gil (ORCID: https://orcid.org/0000-0003-0873-9945)
- Yeon-koo Kang (ORCID: https://orcid.org/0000-0001-6001-2140)
Institutions
- Seoul National University Hospital (KR)
Publication Details
- Journal
- Journal of Cachexia Sarcopenia and Muscle
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1002/jcsm.13730
- Citations
- 1
- Primary Topic
- Peptidase Inhibition and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- Korea Health Industry Development Institute