<scp>Nur77</scp> Promotes Inflammation in Cisplatin‐Induced Acute Kidney Injury Through Transactivation of <scp>SERPINA3</scp> Mediating Wnt/β‐Catenin Pathway

Taken together, our findings revealed that Nur77 knockdown resisted cisplatin-induced HK-2 cells injury through lessening the expression of SERPINA3 mediated by transcriptional regulation and inactivating the Wnt/β-catenin pathway.

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Publication Details

Journal
Nephrology
Published
2025-02-01
DOI
https://doi.org/10.1111/nep.70006
Primary Topic
Nuclear Receptors and Signaling
Type
article
Field-Weighted Citation Impact
0.00
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article

Nur77 Promotes Inflammation in Cisplatin‐Induced Acute Kidney Injury Through Transactivation of SERPINA3 Mediating Wnt/β‐Catenin Pathway

Ying Zhou, Di Xiong, Feiyan Liu, Zhen Wan et al.
Nephrology
Nuclear Receptors and Signaling
article

Nur77 Promotes Inflammation in Cisplatin‐Induced Acute Kidney Injury Through Transactivation of SERPINA3 Mediating Wnt/β‐Catenin Pathway

Ying Zhou, Di Xiong, Feiyan Liu, Zhen Wan, Zhijun Gong
article en

Abstract

Taken together, our findings revealed that Nur77 knockdown resisted cisplatin-induced HK-2 cells injury through lessening the expression of SERPINA3 mediated by transcriptional regulation and inactivating the Wnt/β-catenin pathway.

NephrologyVol. 30(2)
Nanchang University (CN), Third Affiliated Hospital of Nanchang University (CN)
Good health and well-being
Openalex Percentile: Top 96%
Nuclear Receptors and Signaling
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