Potential of Application of Natural Product Nanoparticles in Hypercholesterolemia

Hypercholesterolemia is a condition characterized by high blood cholesterol levels. Currently, the drugs available on the market to treat hypercholesterolemia show adverse side effects, related to their chronic use. Consequently, there is an increased search effort for alternatives and complementary strategies, specifically supplements based on natural products. Moreover, various studies suggest that supplements with high antioxidant activity have a vital role in the prevention of various diseases. In this work, an aqueous avocado extract was prepared and characterized to assess its potential in hypercholesterolemia. Also, a delivery nanosystem using albumin nanoparticles was developed to use this extract as a food supplement.

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Publication Details

Published
2024-11-14
DOI
https://doi.org/10.3390/ecsoc-28-20168
Citations
4
Primary Topic
Natural Antidiabetic Agents Studies
Type
article
Field-Weighted Citation Impact
1.43

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article

Potential of Application of Natural Product Nanoparticles in Hypercholesterolemia

Catarina Pinto Reis, Rita Pacheco, Laura M. Teixeira
4 citations
Natural Antidiabetic Agents Studies
1.43
article

Potential of Application of Natural Product Nanoparticles in Hypercholesterolemia

Catarina Pinto Reis, Rita Pacheco, Laura M. Teixeira
article en
4 citations

Abstract

Hypercholesterolemia is a condition characterized by high blood cholesterol levels. Currently, the drugs available on the market to treat hypercholesterolemia show adverse side effects, related to their chronic use. Consequently, there is an increased search effort for alternatives and complementary strategies, specifically supplements based on natural products. Moreover, various studies suggest that supplements with high antioxidant activity have a vital role in the prevention of various diseases. In this work, an aqueous avocado extract was prepared and characterized to assess its potential in hypercholesterolemia. Also, a delivery nanosystem using albumin nanoparticles was developed to use this extract as a food supplement.

University of Lisbon (PT), Universidade Politécnica de Lisboa (PT)
Centro de Química Estrutural, Fundação para a Ciência e a Tecnologia
Zero hunger
Openalex Percentile: Top 15%
Natural Antidiabetic Agents Studies
1.43
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Potential of Application of Natural Product Nanoparticles in Hypercholesterolemia — Catarina Pinto Reis, Rita Pacheco, et al. · (2024) | TGRS Research Map | TGRS