Tinnitus and Its Comorbidities: A Comprehensive Analysis of Their Relationships

<b>Objectives:</b> This study aimed to explore the demographic and clinical features of tinnitus individuals and analyse its correlation with associated comorbidities. <b>Methods:</b> The study population comprised 147 participants (66 men, 81 women; median age: 52 years) who experienced persistent tinnitus. Comprehensive assessments were carried out, including audiological examinations, scoring using the Tinnitus Handicap Inventory, and thorough medical evaluations. Statistical analyses were applied to explore the correspondences between tinnitus, hearing loss, and various comorbidities, including cardiovascular conditions, metabolic disorders, gastroesophageal reflux disease, autoimmune diseases, pulmonary diseases, and allergic rhinitis. <b>Results:</b> The analysis indicated a slight predominance of females, comprising 55.1% of the participants, with a median onset of tinnitus around the age of 50. Chronic tinnitus was noted, lasting approximately 46 months. Hearing loss was noted in 52.4% of patients, with bilateral tinnitus being the most prevalent type, affecting 44.2% of individuals. Dyslipidaemia was found to significantly predict bilateral tinnitus (<i>p</i> = 0.003*) and left-sided tinnitus (<i>p</i> = 0.023*). Additionally, atherosclerosis was associated with hearing impairment (<i>p</i> = 0.006*) and right-sided tinnitus (<i>p</i> = 0.044*). Dyslipidaemia was also significantly correlated with elevated intensity values (<i>p</i> = 0.04*). Furthermore, atherosclerosis was significantly associated with higher levels of hearing loss (<i>p</i> < 0.00001*). <b>Conclusions:</b> The study emphasises the complex nature of tinnitus and its links to cardiovascular, metabolic, and other comorbidities, highlighting the necessity for comprehensive, interdisciplinary management.

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Publication Details

Journal
Journal of Clinical Medicine
Published
2025-02-15
DOI
https://doi.org/10.3390/jcm14041285
Citations
19
Primary Topic
Hearing, Cochlea, Tinnitus, Genetics
Type
article
Field-Weighted Citation Impact
27.83
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article

Tinnitus and Its Comorbidities: A Comprehensive Analysis of Their Relationships

Panayiota Mavrogeni, Stefani Maihoub, Viktória Molnár, András Molnár
19 citations
Journal of Clinical Medicine
Hearing, Cochlea, Tinnitus, Genetics
27.83
article

Tinnitus and Its Comorbidities: A Comprehensive Analysis of Their Relationships

Panayiota Mavrogeni, Stefani Maihoub, Viktória Molnár, András Molnár
article en
19 citations

Abstract

<b>Objectives:</b> This study aimed to explore the demographic and clinical features of tinnitus individuals and analyse its correlation with associated comorbidities. <b>Methods:</b> The study population comprised 147 participants (66 men, 81 women; median age: 52 years) who experienced persistent tinnitus. Comprehensive assessments were carried out, including audiological examinations, scoring using the Tinnitus Handicap Inventory, and thorough medical evaluations. Statistical analyses were applied to explore the correspondences between tinnitus, hearing loss, and various comorbidities, including cardiovascular conditions, metabolic disorders, gastroesophageal reflux disease, autoimmune diseases, pulmonary diseases, and allergic rhinitis. <b>Results:</b> The analysis indicated a slight predominance of females, comprising 55.1% of the participants, with a median onset of tinnitus around the age of 50. Chronic tinnitus was noted, lasting approximately 46 months. Hearing loss was noted in 52.4% of patients, with bilateral tinnitus being the most prevalent type, affecting 44.2% of individuals. Dyslipidaemia was found to significantly predict bilateral tinnitus (<i>p</i> = 0.003*) and left-sided tinnitus (<i>p</i> = 0.023*). Additionally, atherosclerosis was associated with hearing impairment (<i>p</i> = 0.006*) and right-sided tinnitus (<i>p</i> = 0.044*). Dyslipidaemia was also significantly correlated with elevated intensity values (<i>p</i> = 0.04*). Furthermore, atherosclerosis was significantly associated with higher levels of hearing loss (<i>p</i> < 0.00001*). <b>Conclusions:</b> The study emphasises the complex nature of tinnitus and its links to cardiovascular, metabolic, and other comorbidities, highlighting the necessity for comprehensive, interdisciplinary management.

Journal of Clinical MedicineVol. 14(4)
Semmelweis University (HU), Limassol General Hospital (CY), Straub Medical Center (US), Institute of Aquatic Ecology (HU)
Openalex Percentile: Top 0%
Hearing, Cochlea, Tinnitus, Genetics
27.83
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