<scp>NFAT1</scp> Signaling Contributes to Bone Cancer Pain by Regulating <scp>IL</scp>‐18 Expression in Spinal Microglia

Microglia NFAT1-p38 signaling contributes to bone cancer pain through IL-18-mediated central sensitization in spinal microglia. NFAT1 could be a potential target for therapeutic intervention to prevent bone cancer pain.

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Publication Details

Journal
CNS Neuroscience & Therapeutics
Published
2025-02-01
DOI
https://doi.org/10.1111/cns.70222
Citations
3
Primary Topic
Pain Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
3.49
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article

NFAT1 Signaling Contributes to Bone Cancer Pain by Regulating IL‐18 Expression in Spinal Microglia

Zhouya Xue, Jia‐Yi Zheng, Fengyun Liu, Mingxuan Zhu et al.
3 citations
CNS Neuroscience & Therapeutics
Pain Mechanisms and Treatments
3.49
article

NFAT1 Signaling Contributes to Bone Cancer Pain by Regulating IL‐18 Expression in Spinal Microglia

Zhouya Xue, Jia‐Yi Zheng, Fengyun Liu, Mingxuan Zhu, Dongxu Zhai, Zhiqiang Pan, Zizhu Wang, Qian Chen, Feng Li, Yangyang Chen, Guan Sun, Jixiang Zhu, Ying Zeng, Xue-Tai Chen, Jianzhao Niu
article en
3 citations

Abstract

Microglia NFAT1-p38 signaling contributes to bone cancer pain through IL-18-mediated central sensitization in spinal microglia. NFAT1 could be a potential target for therapeutic intervention to prevent bone cancer pain.

CNS Neuroscience & TherapeuticsVol. 31(2)
Xuzhou Medical College (CN), Nantong University (CN), Yancheng First People's Hospital (CN), Obstetrics and Gynecology Hospital of Fudan University (CN)
Good health and well-being
Openalex Percentile: Top 9%
Pain Mechanisms and Treatments
3.49
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