Population Pharmacokinetics of Prolonged Infusion for Meropenem: Tailoring Dosing Recommendations for Chinese Critically Ill Patients on Continuous Renal Replacement Therapy with Consideration for Renal Function
A population PK model was developed for prolonged meropenem infusion in Chinese CRRT patients, and 0.5 g q6h and 1 g q8h may be the optimal regimen for prolonged infusion.
Authors
- Yaru Peng
- Feifan Xie (ORCID: https://orcid.org/0000-0002-9038-2676)
- Qiang Zhang (ORCID: https://orcid.org/0000-0002-8678-7013)
- Yanan Liu (ORCID: https://orcid.org/0000-0002-0091-7068)
- Sanwang Li (ORCID: https://orcid.org/0000-0001-5979-5133)
- Zeneng Cheng
- Sucui Zhu
Institutions
- Central South University (CN)
- Peking University Shenzhen Hospital (CN)
- Second Xiangya Hospital of Central South University (CN)
- Third Xiangya Hospital (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2025-02-01
- DOI
- https://doi.org/10.2147/dddt.s489603
- Citations
- 3
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 4.18
Funders
- National Natural Science Foundation of China
- Peking University
- Hunan Provincial Innovation Foundation for Postgraduate