Biotransformation of Dehydroepiandrosterone by Aspergillus Species and A Comparison of the Results with Previous Studies

Steroids are widespread in nature, being found in animals, plants, fungi, and certain bacteria. Microbial transformation found wide applications in biotransformation of steroids in order to obtain stereoselective products. This work will explain how to incubate DHEA alongside Aspergillus glaucus MRC 200914 in order to understand the way of this fungus metabolizes the substrate. The main outcome of incubating DHEA with Aspergillus glaucus in this study was the production of several hydroxylated metabolites.

Authors

Publication Details

Journal
Sumerianz Journal of Medical and Healthcare
Published
2025-02-15
DOI
https://doi.org/10.47752/sjmh.81.1.5
Primary Topic
Steroid Chemistry and Biochemistry
Type
article
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article

Biotransformation of Dehydroepiandrosterone by Aspergillus Species and A Comparison of the Results with Previous Studies

Raghda Mahmood Abdulghafoor Al-ani
1 links
Sumerianz Journal of Medical and Healthcare
Steroid Chemistry and Biochemistry
article

Biotransformation of Dehydroepiandrosterone by Aspergillus Species and A Comparison of the Results with Previous Studies

Raghda Mahmood Abdulghafoor Al-ani
article en

Abstract

Steroids are widespread in nature, being found in animals, plants, fungi, and certain bacteria. Microbial transformation found wide applications in biotransformation of steroids in order to obtain stereoselective products. This work will explain how to incubate DHEA alongside Aspergillus glaucus MRC 200914 in order to understand the way of this fungus metabolizes the substrate. The main outcome of incubating DHEA with Aspergillus glaucus in this study was the production of several hydroxylated metabolites.

Sumerianz Journal of Medical and Healthcare(81)
Openalex Percentile: Top 97%
Steroid Chemistry and Biochemistry
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Biotransformation of Dehydroepiandrosterone by Aspergillus Species and A Comparison of the Results with Previous Studies — Raghda Mahmood Abdulghafoor Al-ani · Sumerianz Journal of Medical and Healthcare (2025) | TGRS Research Map | TGRS