Combining Network Pharmacology, Molecular Docking and Experimental Validation to Explore the Effects and Mechanisms of Indirubin on Acute Lymphoblastic Leukemia
The action and mechanism of indirubin in ALL through network pharmacology, as well as in vivo and in vitro experimental validation were elucidated, offering new insights and potential therapeutic avenues for the treatment of ALL.
Authors
- Yinghui Guan (ORCID: https://orcid.org/0000-0003-1801-8332)
- Zhixu He
- Ying Shen (ORCID: https://orcid.org/0000-0003-0656-7377)
- Nianxue Wang
- Lu Jin (ORCID: https://orcid.org/0000-0001-6513-6206)
- Mingyue Wang (ORCID: https://orcid.org/0000-0002-2979-1841)
- Xue Li (ORCID: https://orcid.org/0000-0003-2774-9110)
Institutions
- Guiyang Medical University (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2025-02-01
- DOI
- https://doi.org/10.2147/dddt.s500249
- Citations
- 9
- Primary Topic
- Acute Lymphoblastic Leukemia research
- Type
- article
- Field-Weighted Citation Impact
- 16.91