13N-Ammonia PET-CT for Evaluating Response to Antiangiogenic Therapy and Prognosis in Patients with Advanced Hepatocellular Carcinoma: A Pilot Study
In advanced HCC patients treated with antiangiogenic agents, kinetic parameters from baseline and post-therapy <sup>13</sup>N-ammonia PET-CT may predict early disease progression and survival. PET-CT seems not able to discriminate responders and non-responders after 8-10 weeks of treatment, suggesting the need for future and larger studies after a longer treatment period.
Authors
- Silvia Taralli (ORCID: https://orcid.org/0000-0002-1715-9953)
- Luca Indovina (ORCID: https://orcid.org/0000-0001-8073-9005)
- Enza Genco
- Valentina Scolozzi (ORCID: https://orcid.org/0000-0002-0959-885X)
- Francesca Romana Ponziani (ORCID: https://orcid.org/0000-0002-5924-6238)
- Maurizio Pompili (ORCID: https://orcid.org/0000-0001-6699-7980)
- Amedeo Capotosti
- Alberto Nicoletti (ORCID: https://orcid.org/0000-0003-0658-4310)
- Lucia Leccisotti (ORCID: https://orcid.org/0000-0002-6000-2898)
- Roberto Moretti (ORCID: https://orcid.org/0000-0002-5201-5920)
- Maria Lucia Calcagni
Institutions
- Università Cattolica del Sacro Cuore (IT)
- Agostino Gemelli University Polyclinic (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- Cancers
- Published
- 2025-02-15
- DOI
- https://doi.org/10.3390/cancers17040656
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00