Aerobic exercise improves clearance of amyloid-β via the glymphatic system in a mouse model of Alzheimer's Disease
Swimming training can rescue the function of the glymphatic system, increase the CSF-ISF exchange, promote the polarization distribution of AQP4, and reduce the deposition of Aβ in the hippocampus, thereby improving the learning and memory ability of APP/PS1 mice.
Authors
- Yusi Zhang (ORCID: https://orcid.org/0000-0002-5147-3460)
- Shengxiang Liang
- Lidian Chen (ORCID: https://orcid.org/0000-0002-8699-0839)
- Huawei Lin
- Ling Zheng (ORCID: https://orcid.org/0000-0002-6545-4180)
- Huan‐Huan Liu
- Xiuxiu Wang (ORCID: https://orcid.org/0000-0001-9269-4094)
- Saie Huang (ORCID: https://orcid.org/0009-0000-1490-3241)
- Lixin Peng (ORCID: https://orcid.org/0009-0006-2133-8491)
Institutions
- Fujian University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Brain Research Bulletin
- Published
- 2025-02-18
- DOI
- https://doi.org/10.1016/j.brainresbull.2025.111263
- Citations
- 19
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 17.27