<i>Calculus bovis</i> inhibits liver cancer <i>via</i> the Wnt/β-catenin pathway

In this paper, the mechanism of the Wnt/β-catenin pathway is introduced, and the process and principle of the experiment conducted by Huang <i>et al</i> is explained. We discussed the reliability of the conclusion that <i>Calculus bovis</i> (<i>C. bovis</i>) inhibits M2 tumor-associated macrophage polarization <i>via</i> Wnt/β-catenin pathway modulation to suppress liver cancer. We also offer suggestions for further studies of the use of <i>C. bovis</i> in the treatment of liver cancer.