Combination of Crohn's disease and intestinal tuberculosis. Clinical observation

According to WHO, extrapulmonary forms of tuberculosis (TB) account for 10–15% of the total number of tuberculosis cases worldwide. Crohn's disease (CD) and intestinal tuberculosis have similar clinical, endoscopic and morphological manifestations in many ways. In all cases, when detecting intestinal CD, it is necessary to exclude tuberculosis infection in biopsies using PCR diagnostics. The risk of developing various forms of TB increases with pathogenetic immunosuppressive therapy for inflammatory bowel diseases. A clinical case of a rare combination of the intestinal form of TB and CD is presented, reflecting the difficulty of diagnosing the two pathologies and the difficulty of choosing therapy when they are combined.

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Publication Details

Journal
Terapevticheskii arkhiv
Published
2024-12-27
DOI
https://doi.org/10.26442/00403660.2024.12.203115
Primary Topic
Diagnosis and treatment of tuberculosis
Type
article
Field-Weighted Citation Impact
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article

Combination of Crohn's disease and intestinal tuberculosis. Clinical observation

А И Парфенов, С Г Хомерики, О. В. Князев, Irina G. Pelipas et al.
Terapevticheskii arkhiv
Diagnosis and treatment of tuberculosis
article

Combination of Crohn's disease and intestinal tuberculosis. Clinical observation

А И Парфенов, С Г Хомерики, О. В. Князев, Irina G. Pelipas, K. A. Lesko, И Н Ручкина, A Lishchinskaya, Alina A. Kieva, A N Demchenko
article en

Abstract

According to WHO, extrapulmonary forms of tuberculosis (TB) account for 10–15% of the total number of tuberculosis cases worldwide. Crohn's disease (CD) and intestinal tuberculosis have similar clinical, endoscopic and morphological manifestations in many ways. In all cases, when detecting intestinal CD, it is necessary to exclude tuberculosis infection in biopsies using PCR diagnostics. The risk of developing various forms of TB increases with pathogenetic immunosuppressive therapy for inflammatory bowel diseases. A clinical case of a rare combination of the intestinal form of TB and CD is presented, reflecting the difficulty of diagnosing the two pathologies and the difficulty of choosing therapy when they are combined.

Terapevticheskii arkhivVol. 96(12)
Moscow Clinical Scientific Center (RU), Republican Scientific and Practical Centre of Pulmonology and Tuberculosis (BY)
Openalex Percentile: Top 54%
Diagnosis and treatment of tuberculosis
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