High Rates of “Watch” and “Reserve” Class Antibiotics Used to Treat Infections in Neonates and Infants in Southeast Asia
We evaluated antibiotic prescribing practices for neonates and infants hospitalized with infections in resource-constrained healthcare settings, where antimicrobial resistance is responsible for significant neonatal morbidity and mortality. A point prevalence survey of 667 admitted infants across 10 clinical sites in Southeast Asia revealed a total of 405 antibiotics were prescribed to 218 infants, with high use of World Health Organization-classified "Watch," "Reserve" and "Not Recommended" antibiotics.
Authors
- Maria Esterlita T. Villanueva-Uy (ORCID: https://orcid.org/0000-0002-9155-6893)
- Michelle L. Harrison (ORCID: https://orcid.org/0009-0005-4608-2659)
- Dominicus Husada (ORCID: https://orcid.org/0000-0001-9191-9546)
- Leny Kartina (ORCID: https://orcid.org/0000-0003-0610-0996)
- Hoang Thi Tran (ORCID: https://orcid.org/0000-0001-7729-6063)
- Nambage Shirani Chandrasiri
- Narei Hong (ORCID: https://orcid.org/0000-0002-3781-9939)
- Erena S. Kasahara
- Benjamin F. R. Dickson (ORCID: https://orcid.org/0000-0003-0821-8920)
- Phoebe Williams (ORCID: https://orcid.org/0000-0003-2250-0594)
- Gayana P. S. Gunaratna (ORCID: https://orcid.org/0000-0003-2968-279X)
- Riyadi Adrizain (ORCID: https://orcid.org/0000-0001-6939-3306)
- Huy Nguyen (ORCID: https://orcid.org/0000-0001-7470-0980)
- Chau Hoang Minh Le (ORCID: https://orcid.org/0000-0002-6111-463X)
- Nina Dwi Putri (ORCID: https://orcid.org/0000-0003-0153-9852)
- Siew Moy Fong
- Distyayu Soekardja
Institutions
- The University of Sydney (AU)
- National Institutes of Health (US)
- University of Kelaniya (LK)
- Universitas Airlangga (ID)
- Da Nang Hospital (VN)
- Taronga Conservation Society Australia (AU)
- Philippine General Hospital (PH)
- University of Indonesia (ID)
- University of Science and Technology - The University of Da Nang (VN)
- Colombo North Teaching Hospital (LK)
- Dr. Hasan Sadikin General Hospital (ID)
- Sabah Parks (MY)
- Universitas Dr. Soetomo (ID)
- Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo (ID)
- Health and Human Development (2HD) Research Network (CM)
- Padjadjaran University (ID)
Publication Details
- Journal
- The Pediatric Infectious Disease Journal
- Published
- 2025-01-09
- DOI
- https://doi.org/10.1097/inf.0000000000004614
- Citations
- 2
- Primary Topic
- Antibiotic Use and Resistance
- Type
- article
- Field-Weighted Citation Impact
- 2.52