Comparing approaches to ordering peanut component–resolved diagnostics to reduce the need for oral food challenges
Offering CRD selectively on the basis of clinical characteristics and being guided by a 2-step algorithm are more efficient strategies that can reduce rates of OFC to enhance patient safety, optimize health care resource utilization, and reduce costs. As peanut-specific IgE level and CRD result correlate well, testing for Ara h 2 is likely redundant at very high and low ranges.
Authors
- Michael A. Irvine (ORCID: https://orcid.org/0000-0003-4785-8998)
- Edmond S. Chan (ORCID: https://orcid.org/0000-0003-2947-1175)
- Raymond Mak (ORCID: https://orcid.org/0009-0000-9420-2065)
- James Hethey
- Jian Huang (ORCID: https://orcid.org/0009-0001-4188-4602)
- Li Wang (ORCID: https://orcid.org/0000-0003-0046-4692)
- Sheila Hartstein
Institutions
- University of British Columbia (CA)
- Simon Fraser University (CA)
- BC Children's Hospital (CA)
Publication Details
- Journal
- Journal of Allergy and Clinical Immunology Global
- Published
- 2025-02-15
- DOI
- https://doi.org/10.1016/j.jacig.2025.100440
- Primary Topic
- Food Allergy and Anaphylaxis Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00