Mixing of Tecovirimat in Water to Support Oral Dosing of Infants and Children With Mpox
We demonstrated the 200 mg tecovirimat capsule can be dispersed in 20 mL of water and swirled for 30 or 60 seconds to consistently yield a 10 mg/mL suspension. This finding supports simplified alternative oral dosing of tecovirimat in younger children with mpox.
Authors
- William A. Fischer (ORCID: https://orcid.org/0000-0002-4900-098X)
- Sharon Nachman (ORCID: https://orcid.org/0000-0002-3419-9471)
- Jason Zucker (ORCID: https://orcid.org/0000-0001-6987-6412)
- Timothy Wilkin (ORCID: https://orcid.org/0000-0001-9386-9335)
- Kristina M. Brooks (ORCID: https://orcid.org/0000-0002-3832-8699)
- Grace M. Aldrovandi (ORCID: https://orcid.org/0000-0003-1604-9637)
- Jennifer J. Kiser
- Zixuan Wei (ORCID: https://orcid.org/0000-0001-7016-2775)
Institutions
- University of North Carolina at Chapel Hill (US)
- University of California, Los Angeles (US)
- Cornell University (US)
- Columbia University Irving Medical Center (US)
- University of California System (US)
- University of California San Diego (US)
- Stony Brook Children's Hospital (US)
- University of Colorado Anschutz Medical Campus (US)
- University of Montana (US)
- Columbia University (US)
Publication Details
- Journal
- Journal of the Pediatric Infectious Diseases Society
- Published
- 2025-02-15
- DOI
- https://doi.org/10.1093/jpids/piaf014
- Primary Topic
- Poxvirus research and outbreaks
- Type
- article
- Field-Weighted Citation Impact
- 0.00