Comprehensive Analysis of the Role of Heat Shock Proteins in the Immune Microenvironment and Clinical Significance of Hepatocellular Carcinoma
Our results lead us to conclude that HCC's development and progression are intimately associated with HSPs, and the HRRS model represents a potentially robust prognostic model that could assist in clinical decision-making regarding chemotherapy and immunotherapy for HCC patients. Moreover, HSPD1 and DNAJC5 have the potential to serve as therapeutic targets for HCC.
Authors
- Gang Luo (ORCID: https://orcid.org/0000-0001-9650-4040)
- Naiying Shen (ORCID: https://orcid.org/0000-0002-4345-0744)
- Yanbao Ding
- Han Xiao (ORCID: https://orcid.org/0000-0003-1978-9593)
- Siqi Xiong (ORCID: https://orcid.org/0000-0002-1281-8198)
- Ben Wang (ORCID: https://orcid.org/0000-0002-4134-1835)
- Chunbo Li (ORCID: https://orcid.org/0000-0003-4566-4305)
- Baigen Mei
- Chao Dai
Institutions
- Shanxi Medical University (CN)
- Jiujiang First People's Hospital (CN)
- Shanxi Provincial People’s Hospital (CN)
Publication Details
- Journal
- Journal of Hepatocellular Carcinoma
- Published
- 2025-02-01
- DOI
- https://doi.org/10.2147/jhc.s495151
- Citations
- 1
- Primary Topic
- Heat shock proteins research
- Type
- article
- Field-Weighted Citation Impact
- 0.81