Solanidine‐derived CYP2D6 phenotyping elucidates phenoconversion in multimedicated geriatric patients
Phenotyping of CYP2D6 activity by measurement of diet-derived biomarkers elucidates phenoconversion in geriatric patients. These results might serve as a prerequisite for the validation and establishment of a bedside method to measure CYP2D6 activity in multimorbid patients for successful application of personalized drug prescribing.
Authors
- Thea Laurentius (ORCID: https://orcid.org/0000-0003-1335-2550)
- Anjali A. Roeth (ORCID: https://orcid.org/0000-0002-1670-7487)
- Florian Kahles (ORCID: https://orcid.org/0000-0001-6343-2562)
- Berkan Kurt (ORCID: https://orcid.org/0009-0006-1313-152X)
- Julian Peter Müller (ORCID: https://orcid.org/0009-0002-1505-5664)
- Katja Susanne Just (ORCID: https://orcid.org/0000-0002-6782-8078)
- Julia Stingl (ORCID: https://orcid.org/0000-0002-1566-8156)
- Jens Andreas Sarömba (ORCID: https://orcid.org/0009-0002-9379-4745)
- Cornelius Bollheimer
- Jolanta Tupiec
Institutions
- Carl von Ossietzky Universität Oldenburg (DE)
- RWTH Aachen University (DE)
Publication Details
- Journal
- British Journal of Clinical Pharmacology
- Published
- 2025-02-16
- DOI
- https://doi.org/10.1002/bcp.70004
- Citations
- 4
- Primary Topic
- Health Systems, Economic Evaluations, Quality of Life
- Type
- article
- Field-Weighted Citation Impact
- 12.52
Funders
- B. Braun-Stiftung
- Deutsche Forschungsgemeinschaft
- RWTH Aachen University
- Medizinische Fakultät, RWTH Aachen University