Interplay of Polygenic Risk Score, Smoking Statuses, and Air Pollution on Lung Adenocarcinoma Risk in a Taiwanese Population
PRS significantly predicted lung adenocarcinoma incident cases in a dose-dependent manner among never-smokers. The PRS effect was not noted in smokers. The results were consistent among participants exposed to different air pollution levels.
Authors
- Hui‐Wen Yang
- I‐Chieh Chen (ORCID: https://orcid.org/0000-0002-8345-5304)
- Jeng‐Sen Tseng (ORCID: https://orcid.org/0000-0003-2341-4495)
- Yi‐Ming Chen (ORCID: https://orcid.org/0000-0001-7593-3065)
- Tsung‐Ying Yang
Institutions
- National Yang Ming Chiao Tung University (TW)
- National Chung Hsing University (TW)
- Taichung Veterans General Hospital (TW)
Publication Details
- Journal
- Respirology
- Published
- 2025-02-16
- DOI
- https://doi.org/10.1111/resp.70004
- Citations
- 1
- Primary Topic
- Global Cancer Incidence and Screening
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- Academia Sinica
- Chinese Academy of Sciences
- Taichung Veterans General Hospital
- National Science and Technology Council