Alzheimer’s Disease and Diet

Alzheimer's Disease (AD) is a neurodegenerative disorder characterized by progressive cognitive decline and memory impairment. While the exact cause of AD remains elusive, recent research has suggested that dietary patterns may play a significant role in its onset, progression, and management. This review explores the emerging evidence linking diet to Alzheimer’s Disease, focusing on the impact of specific nutrients and dietary patterns such as the Mediterranean diet, the ketogenic diet, and antioxidants on brain health. We examine the potential mechanisms through which diet may influence neuroinflammation, oxidative stress, amyloid-beta accumulation, and synaptic function. Furthermore, I consider the roles of essential fatty acids, vitamins, minerals, and other bioactive compounds in modulating risk factors associated with AD. The review also highlights the clinical implications and the need for further longitudinal studies to determine the efficacy of dietary interventions as part of AD prevention and management strategies. Understanding the intricate relationship between diet and AD could pave the way for new therapeutic approaches that complement pharmacological treatments and promote healthy aging.

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Publication Details

Journal
Egyptian Journal of Chemistry
Published
2025-02-12
DOI
https://doi.org/10.21608/ejchem.2025.351787.11151
Primary Topic
Diet and metabolism studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Alzheimer’s Disease and Diet

Hebatalla S. Hashem
Egyptian Journal of Chemistry
Diet and metabolism studies
article

Alzheimer’s Disease and Diet

Hebatalla S. Hashem
article en

Abstract

Alzheimer's Disease (AD) is a neurodegenerative disorder characterized by progressive cognitive decline and memory impairment. While the exact cause of AD remains elusive, recent research has suggested that dietary patterns may play a significant role in its onset, progression, and management. This review explores the emerging evidence linking diet to Alzheimer’s Disease, focusing on the impact of specific nutrients and dietary patterns such as the Mediterranean diet, the ketogenic diet, and antioxidants on brain health. We examine the potential mechanisms through which diet may influence neuroinflammation, oxidative stress, amyloid-beta accumulation, and synaptic function. Furthermore, I consider the roles of essential fatty acids, vitamins, minerals, and other bioactive compounds in modulating risk factors associated with AD. The review also highlights the clinical implications and the need for further longitudinal studies to determine the efficacy of dietary interventions as part of AD prevention and management strategies. Understanding the intricate relationship between diet and AD could pave the way for new therapeutic approaches that complement pharmacological treatments and promote healthy aging.

Egyptian Journal of ChemistryVol. 0(0)
National Research Centre (EG)
Openalex Percentile: Top 96%
Diet and metabolism studies
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Alzheimer’s Disease and Diet — Hebatalla S. Hashem · Egyptian Journal of Chemistry (2025) | TGRS Research Map | TGRS