Bio‐Inspired, Miniaturized Magnetic Heart Valve System for Superior Performance Cardiovascular Simulator

The demand for accurate vascular simulators is increasing to facilitate effective clinical studies on cardiovascular diseases. The research presents the miniaturized design and precise programable regulation of an artificial magnetic heart valve inspired by the human aortic valve, demonstrating the diverse types of pulsating waves. The heart valve is constructed using an elastomeric silicone composite embedded with neodymium magnetic micro-particles. This valve system responds rapidly to changes in magnetic fields controlled by miniaturized electromagnets, enabling precise regulation of fluid pressure and flow rate. This allows for the generation of various pressure waveforms and accurately replicates diverse blood pressure changes with a compact design. The design, working mechanism, fabrication process, and optimization of the magnetically controlled biomimetic heart valve are discussed and its performance as a cardiovascular simulator for human and animal models is evaluated. This artificial valve system has the potential to be utilized in humanoid robots to generate heart-like pressure, thereby paving the way for replicating human physiological characteristics. This research promises significant advancements in cardiovascular clinical trials and biomedical research along with the development of humanoid robots and biomimetic mechanical systems.

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Publication Details

Journal
Advanced Materials
Published
2025-02-16
DOI
https://doi.org/10.1002/adma.202419504
Citations
7
Primary Topic
Electrospun Nanofibers in Biomedical Applications
Type
article
Field-Weighted Citation Impact
4.18

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article

Bio‐Inspired, Miniaturized Magnetic Heart Valve System for Superior Performance Cardiovascular Simulator

Gooyoon Chung, Yoonseok Park, Jeongmin Yoo
7 citations
Advanced Materials
Electrospun Nanofibers in Biomedical Applications
4.18
article

Bio‐Inspired, Miniaturized Magnetic Heart Valve System for Superior Performance Cardiovascular Simulator

Gooyoon Chung, Yoonseok Park, Jeongmin Yoo
article en
7 citations

Abstract

The demand for accurate vascular simulators is increasing to facilitate effective clinical studies on cardiovascular diseases. The research presents the miniaturized design and precise programable regulation of an artificial magnetic heart valve inspired by the human aortic valve, demonstrating the diverse types of pulsating waves. The heart valve is constructed using an elastomeric silicone composite embedded with neodymium magnetic micro-particles. This valve system responds rapidly to changes in magnetic fields controlled by miniaturized electromagnets, enabling precise regulation of fluid pressure and flow rate. This allows for the generation of various pressure waveforms and accurately replicates diverse blood pressure changes with a compact design. The design, working mechanism, fabrication process, and optimization of the magnetically controlled biomimetic heart valve are discussed and its performance as a cardiovascular simulator for human and animal models is evaluated. This artificial valve system has the potential to be utilized in humanoid robots to generate heart-like pressure, thereby paving the way for replicating human physiological characteristics. This research promises significant advancements in cardiovascular clinical trials and biomedical research along with the development of humanoid robots and biomimetic mechanical systems.

Advanced MaterialsVol. 37(16)
Kyung Hee University (KR)
Korea Institute of Science and Technology, National Research Foundation of Korea
Good health and well-being
Openalex Percentile: Top 6%
Electrospun Nanofibers in Biomedical Applications
4.18
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