Causal Association of Primary Biliary Cholangitis with Adverse Pregnancy and Neonatal Outcomes: A Two-Sample Mendelian Randomization Study
Our study reveals that genetically predicted PBC is associated with low birth weight, decreased gestational age, and increased risk of preterm labor in a European population. However, current research does not establish a causal relationship between PBC and adverse pregnancy outcomes.
Authors
- Ruifang Li (ORCID: https://orcid.org/0000-0002-7895-9962)
- Yang Xia (ORCID: https://orcid.org/0000-0001-8783-1592)
- Ning Zong
- J. V. K. Tan (ORCID: https://orcid.org/0009-0005-7437-7972)
Institutions
- First Affiliated Hospital of GuangXi Medical University (CN)
Publication Details
- Journal
- International Journal of Women s Health
- Published
- 2025-02-01
- DOI
- https://doi.org/10.2147/ijwh.s494570
- Primary Topic
- Liver Diseases and Immunity
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Medical Research Council
- Division of Graduate Education