Extended Prodromal Period in Herpes Zoster: A Case Report and Management Implications

Herpes zoster typically presents with a prodromal phase of pain lasting three to five days before the appearance of characteristic vesicular lesions. We report a case of herpes zoster in an immunocompetent man in his 70s who experienced an unusually prolonged prodromal period of two weeks. The patient initially presented with radicular pain in the right lower extremity, leading to evaluation for lumbar spinal stenosis. After the appearance of vesicular lesions in the L4-S1 dermatomes, he was diagnosed with herpes zoster and treated with valacyclovir and pregabalin. Despite the delayed initiation of therapy, the patient's symptoms resolved completely without recurrence. This case demonstrates that prolonged prodromal periods can occur in immunocompetent individuals and highlights the importance of maintaining clinical suspicion for herpes zoster in cases of persistent radicular pain. Although our patient recovered well despite treatment delay, prompt initiation of antiviral therapy is recommended once herpes zoster is clinically suspected to ensure optimal outcomes.

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Publication Details

Journal
Cureus
Published
2025-02-16
DOI
https://doi.org/10.7759/cureus.79114
Citations
1
Primary Topic
Herpesvirus Infections and Treatments
Type
article
Field-Weighted Citation Impact
1.35
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article

Extended Prodromal Period in Herpes Zoster: A Case Report and Management Implications

Yuki Kataoka, Hidehiro Someko, Kaori Takamoto
1 citations
Cureus
Herpesvirus Infections and Treatments
1.35
article

Extended Prodromal Period in Herpes Zoster: A Case Report and Management Implications

Yuki Kataoka, Hidehiro Someko, Kaori Takamoto
article en
1 citations

Abstract

Herpes zoster typically presents with a prodromal phase of pain lasting three to five days before the appearance of characteristic vesicular lesions. We report a case of herpes zoster in an immunocompetent man in his 70s who experienced an unusually prolonged prodromal period of two weeks. The patient initially presented with radicular pain in the right lower extremity, leading to evaluation for lumbar spinal stenosis. After the appearance of vesicular lesions in the L4-S1 dermatomes, he was diagnosed with herpes zoster and treated with valacyclovir and pregabalin. Despite the delayed initiation of therapy, the patient's symptoms resolved completely without recurrence. This case demonstrates that prolonged prodromal periods can occur in immunocompetent individuals and highlights the importance of maintaining clinical suspicion for herpes zoster in cases of persistent radicular pain. Although our patient recovered well despite treatment delay, prompt initiation of antiviral therapy is recommended once herpes zoster is clinically suspected to ensure optimal outcomes.

CureusVol. 17(2)
Tohoku University (JP), Kyoto University (JP), Kyoto Medical Center (JP), Kleijnen Systematic Reviews (United Kingdom) (GB), Kyoto City Hospital (JP)
Openalex Percentile: Top 23%
Herpesvirus Infections and Treatments
1.35
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