Comparison of the chondrogenic potential of eBMSCs and eUCMSCs in response to selected peptides and compounds
Based on cell response to the positive control, in the conditions employed in the current study, eBMSCs may be preferred over eUCMSCs for chondrogenesis. The current study supports the use of spheroid culture, and the use of dexamethasone over TGF-β or any of the compounds or peptides tested here from the prior literature to drive chondrogenesis with eBMSCs.
Authors
- J.N. Hatzel
- Peggy A. Keefe
- Laurie R. Goodrich (ORCID: https://orcid.org/0000-0002-8010-4429)
- Emi A. Kiyotake (ORCID: https://orcid.org/0000-0002-6864-3753)
- Michael S. Detamore (ORCID: https://orcid.org/0000-0002-7525-8132)
- Boushra Ajeeb
- Jennifer N. Phillips
Institutions
- Université Bourgogne Franche-Comté (FR)
- University of Oklahoma (US)
- Colorado State University (US)
Publication Details
- Journal
- BMC Veterinary Research
- Published
- 2025-02-16
- DOI
- https://doi.org/10.1186/s12917-024-04448-3
- Citations
- 1
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 1.63
Funders
- University of Oklahoma
- University of Oklahoma Health Sciences Center