Relationship between plasma polymyxin B concentrations and acute kidney injury in critically ill elderly patients: Findings from a prospective study
Monitoring plasma polymyxin B concentrations is essential in elderly patients. Keeping the C<sub>min</sub> below 2.94 mg/L, the C<sub>ss,avg</sub> below 4.14 mg/L, and the AUC<sub>ss,24h</sub> below 99.35 mg h/L may help prevent AKI in this population.
Authors
- Feifei Ye (ORCID: https://orcid.org/0000-0001-7212-3235)
- Wenchao Mao (ORCID: https://orcid.org/0000-0001-5796-5987)
- Kaican Cai (ORCID: https://orcid.org/0000-0003-4664-6694)
- Shijin Gong (ORCID: https://orcid.org/0000-0002-1784-2867)
- Cong Ye (ORCID: https://orcid.org/0000-0003-1547-886X)
- Yihua Yu
- Changyun Zhao (ORCID: https://orcid.org/0000-0002-9828-0295)
Institutions
- Zhejiang Hospital (CN)
Publication Details
- Journal
- Journal of International Medical Research
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1177/03000605251320733
- Citations
- 1
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 1.39