Molecular Crosstalk by miR-449a and miR-34b in endometrial and ovarian cancer cells in vitro

The study demonstrated that these miRNAs could influence critical processes such as angiogenesis, proliferation, inflammation, tumorigenesis, and apoptosis in cancer cells, highlighting their potential as therapeutic targets. However, the varied effects observed with the co-transfection of mimics and inhibitors suggest a complex interplay that requires further investigation.

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Publication Details

Journal
Gene
Published
2025-02-16
DOI
https://doi.org/10.1016/j.gene.2025.149337
Citations
1
Primary Topic
MicroRNA in disease regulation
Type
article
Field-Weighted Citation Impact
0.94
Controls
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article

Molecular Crosstalk by miR-449a and miR-34b in endometrial and ovarian cancer cells in vitro

Anuradha Sharma, Ashwani K. Rana, Indu Sharma, Hanisha
1 citations
Gene
MicroRNA in disease regulation
0.94
article

Molecular Crosstalk by miR-449a and miR-34b in endometrial and ovarian cancer cells in vitro

Anuradha Sharma, Ashwani K. Rana, Indu Sharma, Hanisha
article en
1 citations

Abstract

The study demonstrated that these miRNAs could influence critical processes such as angiogenesis, proliferation, inflammation, tumorigenesis, and apoptosis in cancer cells, highlighting their potential as therapeutic targets. However, the varied effects observed with the co-transfection of mimics and inhibitors suggest a complex interplay that requires further investigation.

GeneVol. 947
Panjab University (IN)
Zero hunger
Openalex Percentile: Top 28%
MicroRNA in disease regulation
0.94
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