Intramyometrial ectopic pregnancy masquerading as intramural leiomyoma: a diagnostic challenge

One of the extremely rare locations for an ectopic pregnancy is myometrium. Intramyometrial ectopic pregnancy is characterised by an unusual form of implantation wherein the gestational sac is situated deep in the myometrium, separated from the endometrial cavity and fallopian tubes. It accounts for <1% of all ectopic pregnancies. The preoperative diagnosis based on ultrasound findings may mimic a degenerated leiomyoma, thereby posing further diagnostic challenges. We report a case of a woman in her late 20s presenting with abnormal uterine bleeding diagnosed ultrasonographically as posterior wall fibroid. Histopathological evaluation of the myomectomy specimen revealed chorionic villi lined by trophoblastic cells, thereby confirming the diagnosis. This case report aims to increase the awareness about the possibility of this potentially life-threatening rare entity even with normal serum beta-human chorionic gonadotropin levels.

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Publication Details

Journal
BMJ Case Reports
Published
2025-02-01
DOI
https://doi.org/10.1136/bcr-2024-262218
Primary Topic
Ectopic Pregnancy Diagnosis and Management
Type
article
Field-Weighted Citation Impact
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article

Intramyometrial ectopic pregnancy masquerading as intramural leiomyoma: a diagnostic challenge

Hephzibah Rani, Ramesh Kumar, Dinesh Shastri, Malashree
BMJ Case Reports
Ectopic Pregnancy Diagnosis and Management
article

Intramyometrial ectopic pregnancy masquerading as intramural leiomyoma: a diagnostic challenge

Hephzibah Rani, Ramesh Kumar, Dinesh Shastri, Malashree
article en

Abstract

One of the extremely rare locations for an ectopic pregnancy is myometrium. Intramyometrial ectopic pregnancy is characterised by an unusual form of implantation wherein the gestational sac is situated deep in the myometrium, separated from the endometrial cavity and fallopian tubes. It accounts for <1% of all ectopic pregnancies. The preoperative diagnosis based on ultrasound findings may mimic a degenerated leiomyoma, thereby posing further diagnostic challenges. We report a case of a woman in her late 20s presenting with abnormal uterine bleeding diagnosed ultrasonographically as posterior wall fibroid. Histopathological evaluation of the myomectomy specimen revealed chorionic villi lined by trophoblastic cells, thereby confirming the diagnosis. This case report aims to increase the awareness about the possibility of this potentially life-threatening rare entity even with normal serum beta-human chorionic gonadotropin levels.

BMJ Case ReportsVol. 18(2)
Sri Dharmasthala Manjunatheshwara College of Dental Sciences & Hospital (IN), Shri Dharmasthala Manjunatheshwara University (IN)
Good health and well-being
Openalex Percentile: Top 96%
Ectopic Pregnancy Diagnosis and Management
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