Therapy response prediction of focal cortex stimulation based on clinical parameters: a multicentre, non-interventional study protocol
This study has received approval from the ethics committee of the University of Freiburg, Germany (23-1540 S1; 23-1183_1-S1-retro). The same approval is applicable for all participating centres in Germany as part of a multicentre study. Ghent University Hospital, Belgium, has received approval for participation in the retrospective arm from their local ethics committee (ONZ-2024-0168). The final approvals for the participating Swiss and Austrian sites are still pending. The results will be made available to the public through peer-reviewed journals and conference presentations.
Authors
- Elisabeth Kaufmann (ORCID: https://orcid.org/0000-0002-7582-2215)
- Ekaterina Pataraia (ORCID: https://orcid.org/0000-0002-1454-7600)
- Felix von Podewils (ORCID: https://orcid.org/0000-0002-3134-8697)
- Susanne Knake (ORCID: https://orcid.org/0000-0002-6298-0513)
- Matthias Dümpelmann (ORCID: https://orcid.org/0000-0002-1476-7777)
- Yaroslav Winter (ORCID: https://orcid.org/0000-0001-9854-4038)
- Josua Kegele (ORCID: https://orcid.org/0000-0002-0126-7466)
- Carlos Martínez Quesada (ORCID: https://orcid.org/0000-0002-2213-7767)
- Hajo M. Hamer (ORCID: https://orcid.org/0000-0003-1709-8617)
- Lukas Imbach (ORCID: https://orcid.org/0000-0002-6135-8642)
- Georg Leonhardt
- Jan Wagner (ORCID: https://orcid.org/0000-0002-0459-8885)
- Bernhard J. Steinhoff (ORCID: https://orcid.org/0000-0001-5995-5862)
- Martin Hirsch (ORCID: https://orcid.org/0000-0002-4496-1458)
- Tim Wehner (ORCID: https://orcid.org/0000-0003-3319-2339)
- Yvonne Weber (ORCID: https://orcid.org/0000-0002-0806-5592)
- Rainer Surges (ORCID: https://orcid.org/0000-0002-3177-8582)
- Jürgen Hesser (ORCID: https://orcid.org/0000-0002-4001-1164)
- Andreas Schulze‐Bonhage (ORCID: https://orcid.org/0000-0003-2382-0506)
- Berthold Voges (ORCID: https://orcid.org/0000-0003-0556-9565)
- Ann Mertens (ORCID: https://orcid.org/0000-0003-2357-9556)
- Christoph Baumgartner (ORCID: https://orcid.org/0000-0003-4766-988X)
- Sotirios Kalousios (ORCID: https://orcid.org/0009-0007-7072-9576)
Institutions
- University of Freiburg (DE)
- Philipps University of Marburg (DE)
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
- Johannes Gutenberg University Mainz (DE)
- Heidelberg University (DE)
- Universitätsmedizin Greifswald (DE)
- University Hospital Bonn (DE)
- Ghent University Hospital (BE)
- University Medical Center Freiburg (DE)
- LMU Klinikum (DE)
- Universitätsklinikum Erlangen (DE)
- Klinik Hietzing (AT)
- University Medical Center of the Johannes Gutenberg University Mainz (DE)
- Bernstein Center for Computational Neuroscience Heidelberg-Mannheim (DE)
- Universitätsklinikum Knappschaftskrankenhaus Bochum (DE)
- Evangelisches Krankenhaus Alsterdorf (DE)
- University and Rehabilitation Clinics Ulm (DE)
- Hertie Institute for Clinical Brain Research (DE)
- Comprehensive Cancer Center Erlangen (DE)
- Epilepsiezentrum Kleinwachau Gemeinnützige (DE)
- Swiss Epilepsy Center (CH)
- Diakonie Kork (DE)
- Karl Landsteiner Society (AT)
- University Hospital Carl Gustav Carus (DE)
- Medical University of Vienna (AT)
- Ludwig-Maximilians-Universität München (DE)
- RWTH Aachen University (DE)
- Ruhr University Bochum (DE)
Publication Details
- Journal
- BMJ Open
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1136/bmjopen-2024-089903
- Citations
- 2
- Primary Topic
- Neurological disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.78
Funders
- Bayer
- Teva Pharmaceutical Industries
- Jazz Pharmaceuticals
- Zogenix
- LivaNova
- GW Pharmaceuticals
- European Commission
- Albert-Ludwigs-Universität Freiburg
- Eisai
- Angelini Pharma
- Arvelle Therapeutics
- UCB Pharma
- Cilag