Comparative Analysis of Sociodemographic, Clinical Features, Laboratory Findings, and Treatment Protocols in Generalized and Localized Cutaneous Lichen Planus

Among the patients with cutaneous LP, 24.7% (n=46) had localized cutaneous LP (LCLP), and 22.5% (n=42) had GCLP. Involvement of the trunk and flexural regions was higher among the patients with GCLP than LCLP (p<0.001 and p=0.012, respectively). Hypertriglyceridemia and hepatitis B core antibody positivity were also observed more frequently in the patients with generalized than LCLP (p=0.005 and p=0.016, respectively). Narrowband ultraviolet B and acitretin were more effective in treating patients with GCLP (p<0.001 and p=0.001, respectively). When the relapse rates in both LP groups were compared, relapses were more frequent in the patients with GCLP (p=0.022). Conclusions: The lesion localization, treatment needs, and relapse rates of patients with GCLP differ from those of patients with LCLP. This article was previously presented as an e-poster at the 32nd National Turkish Dermatology Congress on November 24, 2024.