Enhancing Uses of the Argano (Origanum Vulgare) in Improving Heart Health in Heart Disorders Rats

Background: Cardiovascular diseases (CVD) are the most common cause of death globally, accounting for 30% of deaths. Of these death more than three quants, are a result of coronary heart disease and a stoke. The traditional medicine of Saudi Arabia, which is based on plant treatments, has deep roots in the local community’s understanding of the importance of nu-trition, health, and folk healing. Aim of Study: The objective of the trial was to Enhancing uses of the Argano (Origanum vulgare) in improving heart health in heart disorders rats. Material and Methods: Thirty Sprague-Dawley albino rats, aged 10 weeks, with a weight of 150 pulse or minus 10g, were split into five groups: The 1st was a –ve control (normal), while the other four received adriamycin (ADM) via intraperitoneal injection (5mg/kg) twice weekly for two weeks to induce CVD. Three groups with cardiac disorders were given argano at 5%, 10% and 15% for 28 days, while group one was assumed a reg-ular diet to act as a control positive. The experiment concluded with a blood sample and biochemical examination. Results: The TG, TC, LDL, & VLDL levels in the blood serum of ADM-treated rats were all substantially higher, while the HDL level was significantly lower. There is some evidence that varying doses of argano can help reduce LDL or athero-genic index. Conclusion: It could be concluded that argano has the abil-ity to improve the condition of blood vessels and reduce the risk of CVD through the reduction of harmful lipid profile and increasing the blood antioxidant levels.

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Publication Details

Journal
The Medical Journal of Cairo University/˜The œMedical Journal of Cairo University
Published
2024-12-01
DOI
https://doi.org/10.21608/mjcu.2024.411329
Primary Topic
Drug-Induced Hepatotoxicity and Protection
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article
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article

Enhancing Uses of the Argano (Origanum Vulgare) in Improving Heart Health in Heart Disorders Rats

Ph.D. and LOBNA . SULTAN MASHNAFI
The Medical Journal of Cairo University/˜The œMedical Journal of Cairo University
Drug-Induced Hepatotoxicity and Protection
article

Enhancing Uses of the Argano (Origanum Vulgare) in Improving Heart Health in Heart Disorders Rats

Ph.D. and LOBNA . SULTAN MASHNAFI
article en

Abstract

Background: Cardiovascular diseases (CVD) are the most common cause of death globally, accounting for 30% of deaths. Of these death more than three quants, are a result of coronary heart disease and a stoke. The traditional medicine of Saudi Arabia, which is based on plant treatments, has deep roots in the local community’s understanding of the importance of nu-trition, health, and folk healing. Aim of Study: The objective of the trial was to Enhancing uses of the Argano (Origanum vulgare) in improving heart health in heart disorders rats. Material and Methods: Thirty Sprague-Dawley albino rats, aged 10 weeks, with a weight of 150 pulse or minus 10g, were split into five groups: The 1st was a –ve control (normal), while the other four received adriamycin (ADM) via intraperitoneal injection (5mg/kg) twice weekly for two weeks to induce CVD. Three groups with cardiac disorders were given argano at 5%, 10% and 15% for 28 days, while group one was assumed a reg-ular diet to act as a control positive. The experiment concluded with a blood sample and biochemical examination. Results: The TG, TC, LDL, & VLDL levels in the blood serum of ADM-treated rats were all substantially higher, while the HDL level was significantly lower. There is some evidence that varying doses of argano can help reduce LDL or athero-genic index. Conclusion: It could be concluded that argano has the abil-ity to improve the condition of blood vessels and reduce the risk of CVD through the reduction of harmful lipid profile and increasing the blood antioxidant levels.

The Medical Journal of Cairo University/˜The œMedical Journal of Cairo UniversityVol. 92(12)
Al Baha University (SA)
Good health and well-being
Openalex Percentile: Top 66%
Drug-Induced Hepatotoxicity and Protection
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