The genetic overlap between major depressive disorder, white blood cell counts and interleukin 6
MDD shares genetic underpinnings with immune system components, which implicates immune- mediated pathways in the pathophysiology of MDD. However, this connection may only be relevant for a minority of patients.
Authors
- Olav B. Smeland (ORCID: https://orcid.org/0000-0002-3761-5215)
- Nils Eiel Steen (ORCID: https://orcid.org/0000-0001-6442-1179)
- Piotr Jahołkowski (ORCID: https://orcid.org/0000-0001-9408-3107)
- Pravesh Parekh (ORCID: https://orcid.org/0000-0002-1930-1167)
- Ole A. Andreassen (ORCID: https://orcid.org/0000-0002-4461-3568)
- Erik D Wiström (ORCID: https://orcid.org/0009-0000-4498-9795)
- Alexey A. Shadrin (ORCID: https://orcid.org/0000-0002-7467-250X)
- Srdjan Djurovic (ORCID: https://orcid.org/0000-0002-8140-8061)
- Guy Hindley (ORCID: https://orcid.org/0000-0003-1666-4701)
- Elise Koch (ORCID: https://orcid.org/0000-0003-3727-4470)
- Nadine Parker (ORCID: https://orcid.org/0000-0002-8369-0152)
- Kevin S. O’Connell (ORCID: https://orcid.org/0000-0002-6865-8795)
- Anders M. Dale (ORCID: https://orcid.org/0000-0002-6126-2966)
Institutions
- Oslo University Hospital (NO)
- University of California San Diego (US)
- University of Bergen (NO)
Publication Details
- Journal
- Journal of Affective Disorders Reports
- Published
- 2025-02-15
- DOI
- https://doi.org/10.1016/j.jadr.2025.100889
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00