Dissection of transcriptome and metabolome insights into the polyphyllin biosynthesis in Paris
P. fargesii and P. forrestii are candidate medicinal plants for the development and application of specific polyphyllins. Transcripts from the UGT91 subfamily in Paris may play dual roles, contributing to both the synthesis of polyphyllin II and the catabolism of polyphyllin V and VI. The homologous genes of PpUGT73CE1 may regulate the synthesis of polyphyllin VI in P. fargesii. This study provides new insights into the investigation of biosynthetic pathways in medicinal plants that lack gene clusters.
Authors
- Guowei Zheng (ORCID: https://orcid.org/0000-0001-9820-5685)
- Qi Mi
- Yan Gao (ORCID: https://orcid.org/0000-0001-9406-0538)
- Meifang Yu (ORCID: https://orcid.org/0000-0002-1878-307X)
- Xiaoye Zhang (ORCID: https://orcid.org/0000-0002-3580-8259)
- Xiheng Wan (ORCID: https://orcid.org/0000-0003-0846-3416)
- Xuan Zhang (ORCID: https://orcid.org/0000-0001-6062-6708)
- Jia Chen (ORCID: https://orcid.org/0000-0003-4217-5039)
- Yi‐Chun Chen (ORCID: https://orcid.org/0000-0002-9092-7189)
- Li Q (ORCID: https://orcid.org/0000-0003-3060-3323)
- Ping Xu (ORCID: https://orcid.org/0000-0002-4418-9680)
Institutions
- Yunnan University (CN)
- Yunnan University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- BMC Plant Biology
- Published
- 2025-02-15
- DOI
- https://doi.org/10.1186/s12870-025-06219-0
- Citations
- 4
- Primary Topic
- Phytochemical Studies and Bioactivities
- Type
- article
- Field-Weighted Citation Impact
- 3.22
Funders
- National Natural Science Foundation of China