Integration of Methylation and Gene Expression Deciphered Candidate Biomarkers <scp>DAB2IP</scp> and <scp>SMYD3</scp> in Delayed Encephalopathy After Carbon Monoxide Poisoning
This study, based on dysregulated DNA methylation and gene expression profiles, identified and validated two DEACMP-related genes (DAB2IP and SMYD3) that could serve as epigenetic biomarkers and potential therapeutic targets for DEACMP.
Authors
- Haihua Luo (ORCID: https://orcid.org/0000-0003-4607-9917)
- Lijuan Zhao
- Linlin Hou (ORCID: https://orcid.org/0000-0002-9235-1582)
- Pinpin Jiang (ORCID: https://orcid.org/0000-0001-5680-0742)
- Yanxia Gao (ORCID: https://orcid.org/0000-0001-8490-8494)
- Yue Cheng (ORCID: https://orcid.org/0009-0000-2936-5546)
- Yi W. Li (ORCID: https://orcid.org/0000-0002-7158-3624)
- Yapeng Zhang (ORCID: https://orcid.org/0000-0003-0735-2773)
- Yuan Ding (ORCID: https://orcid.org/0000-0002-9165-7467)
- Yan Zhang (ORCID: https://orcid.org/0000-0003-0680-5443)
- Yuzhen Du (ORCID: https://orcid.org/0000-0002-1539-4247)
- Yong Jiang (ORCID: https://orcid.org/0000-0002-0163-5089)
- Fang Yang (ORCID: https://orcid.org/0009-0006-9446-5117)
- Yue Wu (ORCID: https://orcid.org/0009-0004-2428-0905)
- Huanzhou Zhu
- Hongyi Yan (ORCID: https://orcid.org/0000-0003-4185-0506)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Fudan University (CN)
- Peking Union Medical College Hospital (CN)
- Henan Academy of Sciences (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- CNS Neuroscience & Therapeutics
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1111/cns.70270
- Citations
- 2
- Primary Topic
- Heme Oxygenase-1 and Carbon Monoxide
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Natural Science Foundation of China
- Zhengzhou University
- First Affiliated Hospital of Zhengzhou University
- Key Scientific Research Project of Colleges and Universities in Henan Province