A randomized controlled study protocol of the TOBBI trial: the effect of a 6 weeks intervention with synbiotics on the recovery speed of the gut microbiota after antibiotic treatment in Dutch toddlers
The TOBBI trial was approved by the board of Medical Ethics Review Committee NedMec in June 2022 and registered at https://www.onderzoekmetmensen.nl/en/trial/20358 under the code NL75975.081.20, and at the World Health Organization at https://trialsearch.who.int/Trial2.aspx?TrialID=NL-OMON20358 under NTR-new: NL8996.
Authors
- Anna M. Malinowska (ORCID: https://orcid.org/0000-0002-7402-1328)
- Clara Belzer (ORCID: https://orcid.org/0000-0001-6922-836X)
- Mark J. Alkema (ORCID: https://orcid.org/0000-0002-1311-5179)
- Jan Knol (ORCID: https://orcid.org/0000-0002-2103-5961)
- Kelly Klomp
Institutions
- Nutricia Research (Netherlands) (NL)
- Wageningen University & Research (NL)
Publication Details
- Journal
- BMC Pediatrics
- Published
- 2025-02-15
- DOI
- https://doi.org/10.1186/s12887-025-05405-1
- Citations
- 1
- Primary Topic
- Gastrointestinal motility and disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.81
Funders
- Topconsortium voor Kennis en Innovatie