Urine proteomics-based analysis identifies CHI3L1 as an immune marker and potential therapeutic target for bladder cancer
The present study suggests that CHI3L1 may promote bladder cancer progression through the PI3K-Akt signaling pathway and is associated with M2 macrophage infiltration.
Authors
- Shanhui Liu (ORCID: https://orcid.org/0000-0003-1111-628X)
- Runchun Huang
- Shun Wan
- Siyu Chen (ORCID: https://orcid.org/0000-0003-0680-3894)
- Chenyang Wang (ORCID: https://orcid.org/0009-0005-5002-9690)
- Li Yang (ORCID: https://orcid.org/0000-0002-7880-2113)
- Kunpeng Li (ORCID: https://orcid.org/0000-0001-5805-793X)
Institutions
- Lanzhou University Second Hospital (CN)
- First Hospital of Lanzhou University (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-02-15
- DOI
- https://doi.org/10.1186/s12885-025-13668-1
- Citations
- 1
- Primary Topic
- Peptidase Inhibition and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- Lanzhou University
- Gansu Education Department