Comprehensive single-cell analysis deciphered the immunoregulatory mechanism of TPPU in alleviating sepsis-related acute liver injury
This study demonstrated TPPU's protective efficacy against sepsis-related acute liver injury, underscoring its vital role in modulating liver macrophages and neutrophils and enhancing prospects for personalized immunomodulatory therapy.
Authors
- Yingru Liu (ORCID: https://orcid.org/0000-0002-3784-4886)
- Li Fu (ORCID: https://orcid.org/0000-0001-7761-5618)
- Qingmiao Shi
- Yang Li (ORCID: https://orcid.org/0000-0003-0735-8446)
- Juan Li (ORCID: https://orcid.org/0009-0007-3265-0293)
- Ning Lou (ORCID: https://orcid.org/0000-0002-4920-5037)
- Xue Chen (ORCID: https://orcid.org/0000-0002-7188-3328)
- Mengjuan Xuan
Institutions
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-02-15
- DOI
- https://doi.org/10.1016/j.jare.2025.02.018
- Citations
- 5
- Primary Topic
- Eicosanoids and Hypertension Pharmacology
- Type
- article
- Field-Weighted Citation Impact
- 5.56
Funders
- China Postdoctoral Science Foundation