Cardiovascular function in people with cystic fibrosis on Elexacaftor/Tezacaftor/Ivacaftor: A cross-sectional, observational, single-centre study
This study demonstrated reduced micro- and macrovascular function in pwCF. This dysfunction may have potential health implications, particularly regarding long-term cardiovascular risk and further longitudinal assessments are warranted.
Authors
- Zoe L. Saynor (ORCID: https://orcid.org/0000-0003-0674-8477)
- Kelly A. Mackintosh (ORCID: https://orcid.org/0000-0003-0355-6357)
- Anthony I. Shepherd (ORCID: https://orcid.org/0000-0001-6392-7944)
- T. Daniels (ORCID: https://orcid.org/0000-0002-5249-5100)
- Jo Corbett (ORCID: https://orcid.org/0000-0002-6552-6471)
- Mark I. Allenby (ORCID: https://orcid.org/0000-0001-7403-2097)
- Maria Perissiou (ORCID: https://orcid.org/0000-0002-3974-2250)
- Melitta A. McNarry (ORCID: https://orcid.org/0000-0003-0813-7477)
- Julian Legg (ORCID: https://orcid.org/0000-0002-0960-6231)
- Don S. Urquhart (ORCID: https://orcid.org/0000-0002-9048-9692)
- Gary Connett (ORCID: https://orcid.org/0000-0003-1310-3239)
- L J (ORCID: https://orcid.org/0000-0002-4907-257X)
Institutions
- Royal Hospital for Children (GB)
- Royal Edinburgh Hospital (GB)
- University Hospital Southampton NHS Foundation Trust (GB)
- Swansea University (GB)
- NIHR Southampton Biomedical Research Centre (GB)
- University of Portsmouth (GB)
Publication Details
- Journal
- Journal of Cystic Fibrosis
- Published
- 2025-02-15
- DOI
- https://doi.org/10.1016/j.jcf.2025.02.001
- Citations
- 8
- Primary Topic
- Cystic Fibrosis Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 12.15