Predictive factors for 30-day mortality after polymyxin B treatment of carbapenem-resistant Gram-negative bacilli infections
Polymyxin B AUC<sub>ss,24</sub><sub>h</sub>/MIC of ≥51.3 independently predicted lower 30-day mortality in treating CR-GNB infections. Further studies should verify the AUC<sub>ss,24</sub><sub>h</sub>/MIC target associated with survival outcomes in larger randomized controlled trials.
Authors
- Simin Zhou (ORCID: https://orcid.org/0000-0003-4969-7630)
- Huimin Zhou (ORCID: https://orcid.org/0000-0001-5396-8646)
- Xuemei Luo (ORCID: https://orcid.org/0000-0002-8292-6733)
- Shuo Cheng (ORCID: https://orcid.org/0000-0003-4882-1724)
- Weihong Ge
- Xinyue ShuLai
Institutions
- China Pharmaceutical University (CN)
- Wuhan University (CN)
- Nanjing Drum Tower Hospital (CN)
- Zhongnan Hospital of Wuhan University (CN)
Publication Details
- Journal
- International Journal of Infectious Diseases
- Published
- 2025-02-16
- DOI
- https://doi.org/10.1016/j.ijid.2025.107844
- Citations
- 2
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 1.18