Negative air ions alleviate nicotine-induced renal damage of spontaneously hypertensive rats via inhibiting oxidative stress and TGF-β/Smad pathway
NAIs can attenuated nicotine-exacerbated hypertensive renal damage and fibrosis process through inhibiting oxidative stress and TGF-β/Smad pathway. We suggest that NAIs intervention could be proposed a new approach to adjuvant therapy of chronic kidney disease in smokers with hypertension.
Authors
- Ziqi An (ORCID: https://orcid.org/0000-0002-8544-8749)
- Tianjing Wei
- Mingyang Xiao (ORCID: https://orcid.org/0000-0003-0365-4133)
- Sha Xiao (ORCID: https://orcid.org/0000-0002-1645-4846)
- Na Li
- Jing Zhou (ORCID: https://orcid.org/0009-0007-1644-1694)
- Ziyue Luo (ORCID: https://orcid.org/0009-0006-0108-9088)
- Mingming Shan
- Xiaobo Lu (ORCID: https://orcid.org/0000-0002-7707-7538)
Institutions
- Hainan Medical University (CN)
- China Medical University (CN)
Publication Details
- Journal
- Ecotoxicology and Environmental Safety
- Published
- 2025-02-01
- DOI
- https://doi.org/10.1016/j.ecoenv.2025.117882
- Citations
- 3
- Primary Topic
- Chemical and Physical Studies
- Type
- article
- Field-Weighted Citation Impact
- 4.90
Funders
- Hainan Medical University