Protein Data Bank Japan: Computational Resources for Analysis of Protein Structures
Protein Data Bank Japan (PDBj, https://pdbj.org/) is the Asian hub of three-dimensional macromolecular structure data, and a founding member of the worldwide Protein Data Bank. We have accepted, processed, and distributed experimentally determined biological macromolecular structures for over two decades. Although we collaborate with RCSB PDB and BMRB in the United States, PDBe and EMDB in Europe and recently PDBc in China for our data-in activities, we have developed our own unique services and tools for searching, exploring, visualizing, and analyzing protein structures. We have also developed novel archives for computational data and raw crystal diffraction images. Recently, we introduced the Sequence Navigator Pro service to explore proteins using experimental and computational approaches, which enables experimental structural biologists to increase their insight to help them to design their experimental studies more efficiently. In addition, we also introduced a new UniProt-integrated portal to provide users with a quick overview of their target protein and it shows a recommended structure and integrates data from various internal and external resources. With these new additions, we have enhanced our service portfolio to benefit both experimental as computational structural biologists in their search to interpret protein structures, their dynamics and function.
Authors
- Tsukasa Nakamura (ORCID: https://orcid.org/0000-0002-6312-3070)
- Kengo Kinoshita (ORCID: https://orcid.org/0000-0003-3453-2171)
- Genji Kurisu (ORCID: https://orcid.org/0000-0002-5354-0807)
- Toshiaki Katayama (ORCID: https://orcid.org/0000-0003-2391-0384)
- Chioko Nagao (ORCID: https://orcid.org/0000-0002-7721-0642)
- Gert‐Jan Bekker (ORCID: https://orcid.org/0000-0001-8385-5693)
- Daisuke Kihara (ORCID: https://orcid.org/0000-0003-4091-6614)
- Matsuyuki Shirota (ORCID: https://orcid.org/0000-0002-7776-9964)
Institutions
- High Energy Accelerator Research Organization (JP)
- Tohoku University (JP)
- Purdue University West Lafayette (US)
- Tohoku Medical Megabank Organization (JP)
- Protein Research Foundation (JP)
- Research Organization of Information and Systems (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- Journal of Molecular Biology
- Published
- 2025-02-15
- DOI
- https://doi.org/10.1016/j.jmb.2025.169013
- Citations
- 8
- Primary Topic
- Enzyme Structure and Function
- Type
- article
- Field-Weighted Citation Impact
- 4.14
Funders
- Japan Agency for Medical Research and Development
- National Institutes of Health
- Japan Society for the Promotion of Science
- National Bioscience Database Center