Dapagliflozin in diabetic kidney disease patients with different filtration status
DKD with non-hyperfiltration with SBP ≤ 120 mmHg had a lower mean eGFR decline and greater decrease in the ACR after treatment. The initial increase in FENa and subsequent decrease after dapagliflozin treatment may be the main mechanism behind the eGFR variation.
Authors
- Honghong Zou (ORCID: https://orcid.org/0000-0003-0966-6880)
- Manna Li (ORCID: https://orcid.org/0000-0001-5702-1177)
- Pingping Yang (ORCID: https://orcid.org/0009-0008-3995-1707)
- Yang Yang
- Gaosi Xu
- Li Wang (ORCID: https://orcid.org/0000-0003-3722-5986)
Institutions
- Nanchang University (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- Second Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- European Journal of Pharmaceutical Sciences
- Published
- 2025-02-15
- DOI
- https://doi.org/10.1016/j.ejps.2025.107045
- Citations
- 1
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 1.29
Funders
- National Natural Science Foundation of China