[Predictive Value of the Modified Controlling Nutritional Status Score in Patients with Pathological Stage Ⅰ-Ⅱ-Ⅲ Colorectal Cancer Following Radical Surgery].

This study aimed to assess predictive value of the modified controlling nutritional status(mCONUT)score in patients with pathological Stage(pStage)Ⅰ-Ⅱ-Ⅲ colorectal cancer(CRC)following radical surgery. Patients were classified into 2 groups based on the mCONUT score: those with the mCONUT score of ≤4 as mCONUT-Low group and those with that of ≥5 as mCONUT-High group. Association between the mCONUT score and clinicopathological features was examined. Survival curves of both the 2 groups for overall survival(OS), relapse-free survival(RFS)and disease-specific survival(DSS)were generated using Kaplan-Meier method and compared using the log-rank test, respectively. Multivariate analyses using the Cox proportional hazards model were performed to determine factors related to OS, RFS and DSS, respectively. High mCONUT score was significantly related to female gender, older age, emergency operation, colon cancer, right-sided disease, presence of venous invasion, advanced pStage, relapse and death. Survival curves showed that the mCONUT-High group had significantly worse prognosis than the mCONUT-Low group for OS, RFS and DSS, respectively. Multivariate analyses showed that high mCONUT score was a significantly independent risk factor for worse outcome of OS, RFS and DSS, respectively. In conclusion, the mCONUT score is useful to predict outcome of patients with pStage Ⅰ-Ⅱ-Ⅲ CRC following radical surgery.