[A Case of Conversion Surgery after Nivolumab and Chemotherapy for Metastatic Gastric Cancer].

We report a case of conversion surgery after nivolumab treatment and chemotherapy for metastatic gastric cancer. An 81-year-old man was diagnosed with advanced gastric cancer with enlarged para-aortic lymph nodes and FDG uptake on positron emission tomography. The patient was diagnosed with unresectable gastric cancer and received nivolumab and SOX therapy. After 7 courses of chemotherapy, the primary lesion disappeared with scarring and the para-aortic lymph nodes were reduced. Consequently, we performed a radical gastrectomy with D2 and para-aortic lymph node dissection as a conversion surgery. Histopathological results revealed a complete pathological response in both the primary lesion and lymph nodes, including the para-aortic lymph nodes. The patient did not receive any postoperative adjuvant chemotherapy and has been recurrence-free for 8 months.

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PubMed
Published
2024-12-01
Primary Topic
Gastric Cancer Management and Outcomes
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article
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article

[A Case of Conversion Surgery after Nivolumab and Chemotherapy for Metastatic Gastric Cancer].

Alex Garcez Utsumi, Zenichiro Saze, Shotaro Mochizuki, Tomohiro Kikuchi et al.
PubMed
Gastric Cancer Management and Outcomes
article

[A Case of Conversion Surgery after Nivolumab and Chemotherapy for Metastatic Gastric Cancer].

Alex Garcez Utsumi, Zenichiro Saze, Shotaro Mochizuki, Tomohiro Kikuchi, Akinao Kaneta, Ryo Kanouda, Hajime Matsuida, Hiroyuki Hanayama, Azuma Nirei, Sohei Hayashishita, Yuko Hashimoto, Koji Kono, Hiroya Suzuki
article en

Abstract

We report a case of conversion surgery after nivolumab treatment and chemotherapy for metastatic gastric cancer. An 81-year-old man was diagnosed with advanced gastric cancer with enlarged para-aortic lymph nodes and FDG uptake on positron emission tomography. The patient was diagnosed with unresectable gastric cancer and received nivolumab and SOX therapy. After 7 courses of chemotherapy, the primary lesion disappeared with scarring and the para-aortic lymph nodes were reduced. Consequently, we performed a radical gastrectomy with D2 and para-aortic lymph node dissection as a conversion surgery. Histopathological results revealed a complete pathological response in both the primary lesion and lymph nodes, including the para-aortic lymph nodes. The patient did not receive any postoperative adjuvant chemotherapy and has been recurrence-free for 8 months.

PubMedVol. 51(13)
Fukushima Medical University (JP)
Openalex Percentile: Top 55%
Gastric Cancer Management and Outcomes
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[A Case of Conversion Surgery after Nivolumab and Chemotherapy for Metastatic Gastric Cancer]. — Alex Garcez Utsumi, Zenichiro Saze, et al. · PubMed (2024) | TGRS Research Map | TGRS