Donor-specific anti-HLA antibodies (DSAs) in patients undergoing allogeneic hematopoietic stem cell transplantation from mismatched donors on behalf of GITMO and AIBT.
Anti-HLA antibodies and DSAs were confirmed as risk factors affecting OS. DSAs were managed with various approaches resulting in stable engraftment in 81.9% of patients. Our study supports the clinical relevance of DSAs detection and management in mmHSCT. A standardized approach of DS is warranted.
Authors
- Lia Mele (ORCID: https://orcid.org/0000-0001-7733-6862)
- Paola Carluccio
- Matteo Pelosini (ORCID: https://orcid.org/0000-0002-4151-7132)
- Elena Oldani
- Simone Cesaro (ORCID: https://orcid.org/0000-0002-8698-9547)
- Attilio Olivieri (ORCID: https://orcid.org/0000-0001-9089-9328)
- Alessandra Picardi (ORCID: https://orcid.org/0000-0002-0136-7686)
- Fabio Ciceri (ORCID: https://orcid.org/0000-0003-0873-0123)
- Paolo Bernasconi (ORCID: https://orcid.org/0000-0001-6043-3367)
- Michele Malagola (ORCID: https://orcid.org/0000-0003-0907-130X)
- Giovanni Grillo (ORCID: https://orcid.org/0000-0002-9084-9969)
- Massimo Martino
- Ursula La Rocca (ORCID: https://orcid.org/0000-0002-1990-9973)
- Benedetto Bruno (ORCID: https://orcid.org/0000-0002-7299-6770)
- Lucia Farina (ORCID: https://orcid.org/0000-0002-5219-0673)
- Alfonso Piciocchi (ORCID: https://orcid.org/0000-0001-8648-885X)
- Patrizia Chiusolo (ORCID: https://orcid.org/0000-0002-1355-1587)
- Walter Barberi (ORCID: https://orcid.org/0000-0003-2159-0903)
- Roberto Crocchiolo (ORCID: https://orcid.org/0000-0001-8473-202X)
- Benedetta Mazzi
- Elena Tagliaferri
- Raffaella Cerretti (ORCID: https://orcid.org/0000-0003-3638-0650)
- Maura Faraci (ORCID: https://orcid.org/0000-0001-5715-501X)
- Valeria Miotti
- Riccardo Saccardi (ORCID: https://orcid.org/0000-0002-5763-5467)
- Roberto Ricci (ORCID: https://orcid.org/0000-0003-1259-1699)
- Lucia Prezioso (ORCID: https://orcid.org/0000-0003-1660-4960)
- Anna Grassi (ORCID: https://orcid.org/0000-0001-7273-4263)
- Nicoletta Sacchi (ORCID: https://orcid.org/0000-0002-7164-401X)
- F. Papola (ORCID: https://orcid.org/0000-0003-2644-2395)
- Michele Cimminiello (ORCID: https://orcid.org/0000-0003-1932-0779)
- Michela Cerno
- Francesca Bonifazi (ORCID: https://orcid.org/0000-0003-1544-9911)
- Alida Dominietto (ORCID: https://orcid.org/0000-0001-9143-3714)
- Nicola Mordini (ORCID: https://orcid.org/0000-0002-4969-1434)
- Stella Santarone (ORCID: https://orcid.org/0000-0002-5037-0515)
- Anna Proia
- Anna Paola Iori
- Gianni Rombolà
- Giuseppina De Simone (ORCID: https://orcid.org/0000-0001-9783-5431)
Institutions
- University of Pisa (IT)
- University of Pavia (IT)
- Istituto Giannina Gaslini (IT)
- Ente Ospedaliero Ospedali Galliera (IT)
- Ospedale Antonio Cardarelli (IT)
- Azienda Ospedaliera Universitaria Integrata Verona (IT)
- Ospedale San Carlo (IT)
- Ospedali Riuniti di Ancona (IT)
- Fondazione Gimema Onlus (IT)
- Azienda Ospedaliero-Universitaria Careggi (IT)
- Azienda USL di Bologna (IT)
- Ospedale Santa Maria della Misericordia di Udine (IT)
- Azienda Sanitaria Ospedaliera S.Croce e Carle Cuneo (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- University of Florence (IT)
Publication Details
- Journal
- PubMed
- Published
- 2025-03-01
- DOI
- https://doi.org/10.2450/bloodtransfus.790
- Primary Topic
- Hematopoietic Stem Cell Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 0.00