[A Case of Resection for a Late-Stage Solitary Hepatic Metastasis from Very Early Breast Cancer].

A 57-year-old woman underwent left breast conserving surgery(Bp+Ax)for breast cancer at 46 years of age. Histopathological findings were invasive ductal carcinoma(tubule forming type), pN0(0/17), Ly0, V0, NG1, HG1, pT1aN0M0, Stage Ⅰ, ER 100%, HER2 score 0. Postoperatively, only radiotherapy to the preserved breast was performed and no adjuvant drug therapy was administered. This time, a 45 mm liver tumor in segment 4/3 was found by abdominal ultrasound for health checkup. Enhanced ultrasonography showed poor contrast, CT showed a low density tumor with calcification, MRI showed no diffusion reduction, and PET showed no FDG uptake. Although the findings were not typical for suspecting malignancy, but cholangiocellular carcinoma or metastatic liver cancer could not be ruled out. Laparoscopic liver resection was performed. Histopathological findings revealed liver metastasis of breast cancer. We report a rare case, a late-stage solitary hepatic metastasis from very early breast cancer. Although the concept of breast cancer as a systemic disease is well-established, in this case there is a possibility that recurrence would not have occurred if postoperative adjuvant drug therapy had been performed. The importance of postoperative adjuvant drug therapy for breast cancer was suggested. At present, she remains disease-free after hepatectomy.

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PubMed
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2024-12-01
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Cancer Diagnosis and Treatment
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[A Case of Resection for a Late-Stage Solitary Hepatic Metastasis from Very Early Breast Cancer].

Toshio Tabei, Takashi Nakakuma, Kana Yamasaki, Soichiro Ueno
PubMed
Cancer Diagnosis and Treatment
article

[A Case of Resection for a Late-Stage Solitary Hepatic Metastasis from Very Early Breast Cancer].

Toshio Tabei, Takashi Nakakuma, Kana Yamasaki, Soichiro Ueno
article en

Abstract

A 57-year-old woman underwent left breast conserving surgery(Bp+Ax)for breast cancer at 46 years of age. Histopathological findings were invasive ductal carcinoma(tubule forming type), pN0(0/17), Ly0, V0, NG1, HG1, pT1aN0M0, Stage Ⅰ, ER 100%, HER2 score 0. Postoperatively, only radiotherapy to the preserved breast was performed and no adjuvant drug therapy was administered. This time, a 45 mm liver tumor in segment 4/3 was found by abdominal ultrasound for health checkup. Enhanced ultrasonography showed poor contrast, CT showed a low density tumor with calcification, MRI showed no diffusion reduction, and PET showed no FDG uptake. Although the findings were not typical for suspecting malignancy, but cholangiocellular carcinoma or metastatic liver cancer could not be ruled out. Laparoscopic liver resection was performed. Histopathological findings revealed liver metastasis of breast cancer. We report a rare case, a late-stage solitary hepatic metastasis from very early breast cancer. Although the concept of breast cancer as a systemic disease is well-established, in this case there is a possibility that recurrence would not have occurred if postoperative adjuvant drug therapy had been performed. The importance of postoperative adjuvant drug therapy for breast cancer was suggested. At present, she remains disease-free after hepatectomy.

PubMedVol. 51(13)
Hakodate Central General Hospital (JP)
Openalex Percentile: Top 57%
Cancer Diagnosis and Treatment
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[A Case of Resection for a Late-Stage Solitary Hepatic Metastasis from Very Early Breast Cancer]. — Toshio Tabei, Takashi Nakakuma, et al. · PubMed (2024) | TGRS Research Map | TGRS