[irAE-Related Postoperative Anastomotic Stenosis Following Gastrectomy for Gastric Cancer].

Despite recent advances in chemotherapy with immune-checkpoint inhibitor(ICI), some patients may have to undergo surgery after the immune-related adverse events(irAE). We report here a case of a 61-year-old man who developed the irAE-related anastomotic stenosis after robotic gastrectomy for gastric cancer. Previously, he was diagnosed as double cancers of far-advanced hung cancer and gastric cancer. He was treated with ICI-based chemotherapy comprising CBDCA, PEM and pembrolizumab for lung cancer, and developed drug-induced pneumonia and dermatomyositis due to severe irAE. Stenosis was improved with steroid therapy. Until now, there has been no recurrence without symptoms in these 2 years.

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PubMed
Published
2024-12-01
Primary Topic
Gastric Cancer Management and Outcomes
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article
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article

[irAE-Related Postoperative Anastomotic Stenosis Following Gastrectomy for Gastric Cancer].

Fumihiro Taniguchi, Shuhei Komatsu, Jun Ikeda, Yusuke Uozumi et al.
PubMed
Gastric Cancer Management and Outcomes
article

[irAE-Related Postoperative Anastomotic Stenosis Following Gastrectomy for Gastric Cancer].

Fumihiro Taniguchi, Shuhei Komatsu, Jun Ikeda, Yusuke Uozumi, Yasuhiro Shioaki, Itsuko Shibata, Hiroyuki Kanazawa, Tomoki Konishi, Ryo Takeda, Katsumi Shimomura, Koji Soga
article en

Abstract

Despite recent advances in chemotherapy with immune-checkpoint inhibitor(ICI), some patients may have to undergo surgery after the immune-related adverse events(irAE). We report here a case of a 61-year-old man who developed the irAE-related anastomotic stenosis after robotic gastrectomy for gastric cancer. Previously, he was diagnosed as double cancers of far-advanced hung cancer and gastric cancer. He was treated with ICI-based chemotherapy comprising CBDCA, PEM and pembrolizumab for lung cancer, and developed drug-induced pneumonia and dermatomyositis due to severe irAE. Stenosis was improved with steroid therapy. Until now, there has been no recurrence without symptoms in these 2 years.

PubMedVol. 51(13)
Kyoto first Red Cross hospital (JP), Japanese Red Cross Society Kyoto Daini Hospital (JP)
Openalex Percentile: Top 55%
Gastric Cancer Management and Outcomes
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[irAE-Related Postoperative Anastomotic Stenosis Following Gastrectomy for Gastric Cancer]. — Fumihiro Taniguchi, Shuhei Komatsu, et al. · PubMed (2024) | TGRS Research Map | TGRS